Pyridines and derivatives
- (4)
- (1)
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- (22)
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- (1)
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- (50)
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- (1)
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- (1)
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- (1)
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- (1)
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- (1)
- (1)
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- (1)
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- (1)
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- (1)
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- (1)
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- (7)
- (5)
- (1)
- (1)
- (3)
- (5)
- (10)
- (2)
- (1)
- (6)
- (6)
- (7)
- (12)
- (1)
- (1)
- (39)
- (1)
- (12)
- (11)
- (4)
- (2)
- (2)
- (15)
- (15)
- (1)
- (1)
- (1)
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- (9)
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- (1)
- (1)
- (3)
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- (3)
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- (1)
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- (1)
- (1)
- (1)
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- (3)
- (1)
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- (5)
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- (1)
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- (1)
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- (1)
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- (1)
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Medchemexpress LLC Valomaciclovir stearate | 195156-77-5 | 97.0% | 618.85 | 1 MG
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Valomaciclovir stearate (ABT 606) is a nucleoside analog and the prodrug of Omaciclovir. It exhibits antiviral activity against HSV-1 and varicella zoster virus (VZV).
- Nucleoside analog
- Omaciclovir prodrug
- Antiviral activity against HSV-1
- Antiviral activity against varicella zoster virus (VZV)
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC m-PEG12-azide | 2170098-29-8 | MFCD13184959 | 98.6% | C25H51N3O12 | 1 G
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m-PEG12-azide is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, featuring an Azide group.
- Undergoes copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups.
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PROTACs degrade target proteins by exploiting the intracellular ubiquitin-proteasome system.
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Medchemexpress LLC Cinobufagin | 470-37-1 | 442.54 | 1 ML
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Cinobufagin is an anticancer agent derived from the Asiatic toad, Bufo gargarizans. It functions by inducing cell cycle arrest in either the G1 or G2/M phases, which subsequently leads to apoptosis in cancer cells. Studies have shown that Cinobufagin can inhibit tumor growth in mouse models with melanoma and glioblastoma multiforme xenografts.
- Anticancer agent.
- Induces cell cycle arrest in cancer cells (G1 or G2/M phase).
- Leads to apoptosis in cancer cells.
- Inhibits tumor growth in melanoma and glioblastoma multiforme xenograft mouse models.
- Purity: 99.69%.
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Medchemexpress LLC En450 Nf-κb degrader | 793719-01-4 | 98.6% | C11H13ClN2O3S | 5 MG
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EN450 is a cysteine-reactive covalent molecular glue degrader that targets NF-κB. It interacts with the allosteric C111 in the E2 ubiquitin ligase UBE2D and induces the formation of a ternary complex between UBE2D and NFKB1. This compound achieves its anti-proliferative effects through a Cullin E3 ligase and proteasome-dependent mechanism, significantly inhibiting the proliferation of HAP1 leukemia cancer cells and HEK293T cells, and reducing the levels of the p105 and p50 subunits of NFκB1.
- Targets Nf-κb
- Interacts with allosteric C111 in the E2 ubiquitin ligase UBE2D
- Induces ternary complex formation between UBE2D and NFKB1
- Achieves anti-proliferative effects via Cullin E3 ligase and proteasome-dependent mechanism
- Inhibits proliferation of HAP1 leukemia cancer cells and HEK293T cells
- Reduces levels of p105 and p50 subunits of NFκB1
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Medchemexpress LLC Chlormethiazole hydrochloride | 6001-74-7 | MFCD00673948 | 99.94% | C6H9Cl2NS | 50 MG
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Chlormethiazole hydrochloride is a potent and orally active GABAA agonist. It functions by inhibiting cytochrome P450 isoforms CYP2A6 and CYP2E1 in human liver microsomes. This compound acts as an anticonvulsant agent and shows potential for treating convulsive status epilepticus.
- Potent and orally active GABAA agonist
- Inhibits cytochrome P450 isoforms (CYP2A6 and CYP2E1)
- Acts as an anticonvulsant agent
- Demonstrates potential for treating convulsive status epilepticus
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Medchemexpress LLC Dihomo-r-Linolenic a 5mg | 21061-10-9 | 322.53 g·mol⁻¹ | C21H38O2 | 5 MG
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Dihomo-γ-linolenic acid methyl ester is an n-6 polyunsaturated fatty acid methyl ester used as a research reagent. It is a metabolic precursor in the arachidonic acid pathway and is metabolized to anti-inflammatory eicosanoids such as prostaglandin E1. This highly purified compound is intended for biochemical and pharmacological studies investigating eicosanoid metabolism and inflammatory signaling.
- High purity: ≥98%.
- CAS number 21061-10-9.
- Small-quantity research format (e.g., 5 MG aliquots in solvent).
- Used for studies of eicosanoid metabolism and anti-inflammatory pathways.
- Provided as a methyl ester derivative for lipid research workflows.
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Medchemexpress LLC β-D-Glucopyranosiduronic, 5-hydroxy-8-methoxy-4-oxo-2-phenyl-4H-1-benzopyran-7-yl | 51059-44-0 | 460.39 | 1 ML
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Wogonoside, a flavonoid glycoside isolated from Huangqin, possesses anti-inflammatory effects and induces autophagy in breast cancer cells by regulating the MAPK-mTOR pathway.
- Isolated from Huangqin.
- Possesses anti-inflammatory effects.
- Induces autophagy in breast cancer cells.
- Regulates the MAPK-mTOR pathway.
- Purity of 99.91%.
- Appearance is light yellow to yellow solid.
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Medchemexpress LLC CC214-1 | 1021920-32-0 | C20H21N7O2 | 1 ML
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CC214-1 is an efficacious mTOR inhibitor that induces autophagy with an IC50 of 0.002 μM. This compound serves as an in vitro tool for exploring mTOR kinase biology and can be used in glioblastoma studies.
- Efficacious mTOR inhibitor
- Induces autophagy
- IC50 of 0.002 μM for mTOR
- Inhibits mTORC2 and mTORC1 signaling in PC-3 cells
- Can be used for glioblastoma studies
- Synergizes with rapamycin to inhibit tumor cell proliferation
- Efficiently inhibits T cell activation
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Cambridge Isotope Laboratories JECS PCB/POPs/PBDE Calibration Standard (CS5L) 0 25 mL
JECS PCB/POPs/PBDE Calibration Standard (CS5L) 0 25 mL
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5000695217 2 5-FURANDICARBOXALD 25MG
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5000695222 IZMYND8-34 5MG
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5000695233 TALTOBULIN INTERMEDI 25MG
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5000695363 3-4-BROMOBENZOYLPR 1G
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5000695375 3-TRIFLUOROMETHYLB 1KG
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000695919 SMCC 100MG
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